Roche stock: analysis & valuation

RO.SWISIN US7751331015Drug Manufacturers - GeneralSwitzerlandData as of Nov 10, 2026
Metrics analysis · Drug Manufacturers - General

Roche RO.SW

Price 410.40 CHF +0.10%Market cap 327.0 bn CHF52 weeks 292.00 – 415.60
Forward P/E
18.6x
Industry 16.4x
EV/EBITDA
14.8x
Industry 13.4x
Revenue growth
-1.2%
Industry 5.6%
Operating margin
36.2%
Industry 34.3%
Return on equity
38.1%
Industry 20.0%
Free cash flow yield
3.2%
Industry 4.4%

What does Roche do?

Roche is a Swiss healthcare group based in Basel and one of the world's largest pharmaceutical and diagnostics companies. The business is divided into two divisions: Pharmaceuticals and Diagnostics. The pharmaceuticals division develops and markets prescription drugs, mainly in oncology, neurology, immunology, ophthalmology and rare diseases. Customers include hospitals, physicians, pharmacies, and public and private payers.

The diagnostics division supplies laboratory tests, analyzers and digital solutions for the early detection, diagnosis and treatment monitoring of diseases. A large share of revenue here comes from consumables used continuously on installed instruments. Competitively, Roche benefits from combining both divisions, which enables personalized medicine: diagnostic tests help identify suitable patients for targeted therapies. The company also has high research intensity, a broad product pipeline and biotechnology expertise, partly through its stake in Genentech. Competitors are other large groups in the pharmaceutical and diagnostics industries.

Score profile

Quality6.7
Valuation4.6
Growth2.8
Financial strength3.9
Momentum9.0

Rank vs. Drug Manufacturers - General (15 companies). 10 = top of the group, 5 = middle. Calculated from the metrics below, without AI.

Metrics compared with the industry

On profitability and quality, Roche ranks above average in the group Drug Manufacturers - General (6.7/10). On growth, the company ranks below average in the group Drug Manufacturers - General (2.8/10). On valuation (higher = cheaper), the stock ranks in the middle in the group Drug Manufacturers - General (4.6/10). On financial strength, Roche ranks below average in the group Drug Manufacturers - General (3.9/10).

MetricStockGroup medianRanking
Forward P/E18.6x16.4xbetter than 23 %
Trailing P/E26.8x32.3xbetter than 65 %
PEG ratio1.8x3.3xbetter than 82 %
EV/EBITDA14.8x13.4xbetter than 37 %
Price/sales5.2x4.4xbetter than 43 %
Price/book10.0x6.8xbetter than 25 %
Revenue growth-1.2%5.6%better than 10 %
Earnings growth-7.7%-5.3%better than 46 %
Gross margin74.2%74.2%better than 50 %
Operating margin36.2%34.3%better than 70 %
Net margin19.6%15.7%better than 77 %
Return on equity38.1%20.0%better than 70 %
Debt/equity90.7%119.9%better than 57 %
Current ratio1.2x1.4xbetter than 30 %
Free cash flow yield3.2%4.4%better than 30 %
Dividend yield2.4%2.2%–
Payout ratio63.9%60.8%–
Beta0.320.37–

Valuation: what is Roche worth?

Two valuation approaches – a discounted cash flow model and a valuation at the industry’s median multiples – give Roche a model range of 186.96 CHF to 368.26 CHF per share.

Price 410.40 CHF
Fair value range 186.96 CHF – 368.26 CHFMidpoint 303.93 CHF (−25.9% vs. price)

The full DCF matrix, the reverse DCF (what growth the price implies) and scenarios are part of the Pro analysis.

What the business depends on

  • The success of patent-protected drugs, particularly in oncology, determines the majority of revenue and earnings.
  • New active ingredients from in-house research and acquisitions help replace products losing exclusivity over the long term.
  • Recurring revenue from test consumables on installed analyzer systems stabilizes the diagnostics business.

Risks

  • Patent expiries and the market entry of biosimilars can significantly reduce sales of established core products.
  • Clinical trials can fail or approvals can be delayed, which devalues high development investments.
  • Pricing pressure and regulatory intervention by healthcare systems, as well as currency fluctuations, weigh on margins and reported results.

What to look for with Roche

The share of revenue from new products relative to expiring ones is informative, as it shows how well the pipeline offsets patent losses.

Full AI analysis of Roche

The AI evaluates all the numbers above and turns them into an assessment with a score, strengths and weaknesses, a fair value range and risks – from €2, and in the Pro version (€10) with moat, peer comparison, DCF and scenarios. See an example.

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Frequently asked questions about Roche stock

What is the P/E ratio of Roche stock?

Based on expected earnings, Roche trades at a P/E of 18.6x, compared with a median of 16.4x for the peer group Drug Manufacturers - General. Based on the earnings of the last twelve months it is 26.8x. (data as of Nov 10, 2026)

Does Roche pay a dividend?

Yes. The dividend yield is currently 2.4%, with a payout ratio of 63.9% of earnings.

Is Roche stock undervalued?

Measured by valuation metrics (P/E, EV/EBITDA, price/sales, PEG), Roche is currently valued roughly in line with the average of the companies in the group Drug Manufacturers - General (valuation score 4.6 out of 10). Our model calculations (DCF and industry multiples) give a range of 186.96 CHF to 368.26 CHF per share at a price of 410.40 CHF. This is a model calculation, not an investment recommendation.

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All information without guarantee. Metrics from public market data, updated daily; company profile written editorially with the help of AI. Not investment advice and not a solicitation to buy or sell securities.